Friday, June 29, 2012

Worried about the side effects of cancer recovery drug Tamoxifen and chose to ...

  • Miss Sewart’s diet bans dairy and meat and contains frozen berries, vegetables and spices such as garlic, turmeric and ginger
  • She says turmeric ‘makes cancer cells commit suicide’
  • Worried about the side effects of cancer recovery drug Tamoxifen and chose to change her diet and exercise routines instead

By
Luke Salkeld and Fiona Macrae

14:30 EST, 24 June 2012

|

01:42 EST, 25 June 2012

Vicky Sewart, pictured in her jewellery shop in Plymouth, opted to treat her condition with a health regime involving exercise and special foods

Vicky Sewart, pictured in her jewellery shop in Plymouth, opted to treat her condition with a health regime involving exercise and special foods

A breast cancer patient refused to take powerful drugs she  was offered to stop the disease returning – and chose to depend on a spicy low-fat diet instead.

Following surgery, Vicky Sewart, 44, was worried about possible side-effects from taking the medication.

So instead, she launched herself into a health regime of exercise and specially chosen foods, including turmeric, which she claims 'makes cancer cells commit suicide'.

Experts have warned there is little scientific evidence to back up her claims.

But Miss Sewart believes that the diet she followed after undergoing chemotherapy, radiotherapy and surgery was a vital part of her recovery from the disease.

Her experience will now form part of an academic study into how lifestyle can affect the body's response to cancer.

After she was diagnosed, Miss Sewart did her own research into which foods might have a positive impact on her recovery.

And following an operation to remove a breast and lymph node four years ago, she told doctors she would not take Tamoxifen during remission but would be following her own 'anti-cancer' diet instead.

She said: 'It's very unusual for breast cancer patients not to take the drug.

'When I told the doctors I didn't want to take it, they just advised me to keep oestrogen out of my body, which is basically what the drug does.

‘The doctors absolutely will not say that the diet is going to do anything to help the cancer in any way, other than to say a healthy diet is going to help in the fight against any disease.

Recovering: A picture of Vicky in Antigua, 2008. Concerned about the side-effects of medical drug Tamoxifen Ms Sewart, 44, designed a vegan, diary free diet which included a range of superfoods from frozen berries to curry spices

Recovering: A picture of Vicky in Antigua, 2008. Concerned about the side-effects of medical drug Tamoxifen Miss Sewart, 44, designed a vegan, diary free diet which included a range of superfoods from frozen berries to curry spices

This was four years ago and I think
attitudes are changing a bit now so that these ideas are running
alongside the more usual treatments.

‘I believe absolutely enormously that my diet has assisted my recovery.'

Explaining her decision not to take
Tamoxifen, she went on: 'It was the worry  of the drugs and the side
effects, I didn't want to have to worry about it, I wanted  to be free.'

Turmeric, a spice used when making curry dishes

Turmeric, a spice used when making curry dishes

The jewellery designer and gallery
owner started her health regime with a mostly organic vegan diet,
cutting out all dairy products, adding plenty of 'super-foods', and
taking moderate exercise.

She said: 'Fresh fruit, vegetables
and juices are great, and frozen berries are fantastic as a super-food.
Turmeric kind of makes cancer cells commit suicide and ginger and garlic
are great to cook with.'

For the past four years, Miss Sewart
has provided blood and urine samples and filled in regular
questionnaires as part of national research into how lifestyle can help
prevent the recurrence of breast cancer after surgery.

The largest study of its kind in the world, it involves 56 hospitals around the UK and 3,400 patients who have had the disease.

The full results will be published next year.

Meanwhile, Miss Sewart, from
Plymouth, is hoping to mark her five-year remission next summer and is
due to marry later this year.

Describing her experience of cancer, she added: 'People can die, or come back from it and enjoy life.

‘You've just got to be thankful you're still around.'

Strawberries is a superfood

Ms Sweart used ginger root in her diet

Vicky Sweart used both frozen berries like strawberries and ginger root in her diet which she claims has helped recovery from breast cancer

However, experts urged other cancer sufferers not to abandon conventional treatments.

Sara Hiom, of Cancer Research UK,
said: 'It's not recommended that alternative therapies are  used in
place of conventional medical therapy.

'There is little scientific or
medical evidence to indicate that alternative therapies are more
effective than the proven treatments used by cancer specialists on the
NHS.

‘We would urge anyone to talk to their specialist if they're contemplating them.'

Dr Steve Kelly, who specialises  in
breast cancer at Derriford Hospital in Plymouth, said: 'Breast cancer
deaths have been going down steadily for over 20 years thanks to
surgery, chemotherapy and radiotherapy.

'But there are three things patients can do to help themselves. It doesn't guarantee survival, but it does help.

'The first is to exercise for 30
minutes, three days a week. The second is to not gain any weight, and
the third is to reduce fat intake.

'These things help to reduce the chance of cancer coming back. For this patient, four years on now, it is still early days.' 

He added: 'My job is not to make people have Tamoxifen, but advise people of the risks and benefits.

‘Treatment comes down to a patient, and height, weight and exercise levels are helpful in making a decision.'

Tamoxifen is Britain's most
widely-used breast cancer drug,  given to more than half of patients to
stop tumours from returning after surgery.

The tablets, which cost as little as
aspirin and are taken for up to five years, also prevent the development
of new tumours in an unaffected breast.

The drug, originally developed as a
contraceptive, is the gold standard treatment for breast cancer and has
been given to millions around the world since the 1980s.

It works by blocking the female sex hormone oestrogen from fuelling the growth of tumours.

Used after surgery, it cuts the odds of the tumour returning by around 30 per cent. However, it does not work in all cases.

In contrast, the evidence for curry
spices such as turmeric beating cancer mainly comes from the study of
cells in a dish – while evidence from the treatment of actual patients
is sparse.

In laboratory studies it seems to be
able to kill cancer cells and prevent more from growing, particularly in
breast, bowel, stomach and skin cancers.

It has also been shown to appear to stop the spread of breast cancer cells to other parts of the body in mice.

Here’s what other readers have said. Why not
debate this issue live on our message boards.

The comments below have not been moderated.

//85% of oncologists admit they would not have conventinal cancer treatment IE chemo and radiation//…..The reason for that is that they understand the discomfort of the treatment and the often very low chance of actually beating the disease. These oncologists have also said they would prefer simply to be made comfortable as they wait to die Don’t recall any saying they’d trust in alternative therapies to cure cancer Their point was that the chance of actually beating the disease was often slight. The quality of life in the last months and years of life was their concern.

I remember the recent report in the press about how colloidal silver is now seriously being accepted as a genuine adjunct to allopathic cancer therapy. In leukemia, colloidal silver killed 98% of blood cancer cells in 24 hours in an American study about 10 years ago. Hydrazine Sulphate, Cesium Chloride, laetrile, oxygen therapies, organic food, exercise, not wearing bras at night (allowing full blood lymph circulation- avoid breast cancer), avoiding chemical birth control and abortions (these affect estrogen levels leading to higher incidence of cancer). Also venus fly trap and cat’s claw combined is a great therapy, also see how hemp is curing people in the YouTube video ‘run from the cure’. There are many other therapies that can all play a part in healing, DMSO, chi gung (gong) , enzyme therapies such as antineoplaston therapy, which was proven very successful by Dr Burzynski, yet heavily suppressed by the FDA in America to protect the pharmaceutical industries financial interests.

I am amazed and saddened at all the red arrows following my comment on how raw milk containing colostrum has been successfully used to cure leukemia. Were the red arrows from mindless trolls, or representatives of the pharmaceutical industry? Because to reject that very genuine therapy and thus discourage leukemia sufferers from considering that alternative is not a good thing. I mentioned this therapy to another acquaintance with leukemia who, like the red arrow people here decided not to try the alternative therapy. He only followed his oncologists advice to stop using all milk produce, he did not even consider that raw milk might really be any different. He was a work colleague of mine who then stuck to standard allopathic care, and very rapidly went downhill, dying a few months later, when, if he had tried what i suggested, he might well have lived, and avoided much suffering.

As a large survey of the benefits of chemotherapy showed a benefit of just 1.4% in the US and 1.6% in Australia, for chemo in breast cancer,[1] turmeric or anything else certainly would have a job to be any worse. And with none of the life-destroying side effects of conventional chemo, I am surprised that more women don’t do a bit of research and take an alternative course.
1. Morgan G, et al. The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies. Clinical Oncology 2004; 16: 549-560.

More than a thousand views of “CANCER – THE FORBIDDEN CURES” since yesterday, just shows there are a lot of open minded people around. Thankyou Vicky for the inspiration.

I am taking Tamoxifen for breast cancer, after having a mastectomy with reconstruction, chemo and radiotherapy. I also include a Turmeric supplement, a Vitamin D supplement, B17 (Apricot Kernels), a good multivitamin and organic fruit and vegetables in my diet (especially red peppers and tomatoes), together with exercise. Tamofixen can cause terrible side-effects, including induced menopause, night sweats, hot flushes and aching limbs. Having followed the conventional treatment regimen, I now wish to include other, beneficial supplements and ‘alternative’ approaches in my fight to stop the cancer returning. This lady has exercised her right to choose how she lives here life following her cancer diagnosis. Good luck to her, and, as for the gentleman who pronounced cancer ‘a myth’, I sincerely hope you are never diagnosed, as you will swiftly discover that there is nothing ‘mythical’ about cancer!

She is right to avoid milk products if they are pasteurized, as all the anti cancer compound contained in it known as colostrum will have been destroyed by pasteurization. Raw milk still contains colostrum however, and cow milk has been successfully used to cure leukemia. An acquaintance of mine had a friend who had leukemia, and he was advised by an ayurvedic medical practitioner to move from England to Vrindavan in India and live on nothing but raw cow milk for one year to cure himself of leukemia, and it worked. Other examples can be found on the internet who have used raw cow milk as therapy for leukemia.

‘The China Study’….read it.

Very interesting, ive heard this before, I was due to have chemo after xmas, but brought a health band from ionic-now.co.uk went to start chemo but they said it had gone down so i had started tumeric as well now and its low enough not to start chemo

Completely Average, Somewhere: Some ‘backwater country’ as you call it may have lower survival rates due to unclean water etc. There is more than one factor at play here. I would change your name to below average if I were you :)

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Sleep and the Talkative Mind

Last night, I had a very difficult time getting to sleep. I was quite tired, as I hadn't slept much the night before, but I couldn't turn off my brain. My thoughts continued to race, and I could not quiet them. There was nothing actually preventing me from sleeping – I wasn't particularly worried about anything, nor had I been drinking caffeine. It was simply the clatter of my noisy thoughts preventing me from relaxing and winding down.

This led me to think about (yes, more thoughts!) the tangible impacts that thoughts can have. Thoughts are real, of course, but they do not always spring from an external reality. They are formed in our minds, often as the result of insecurities, anxieties, or merely being too wired, as I was last night. Yet their effects can be all too real. Negative thought patterns can cause us hold ourselves back in many areas of life. They can make us feel afraid, inadequate , or insecure. Yet the thoughts themselves are nothing more than mental formations.

It is for that reason that meditation is important. Gaining the ability to examine our thoughts and recognize them for what they are allows us to determine which thoughts are constructive and which are not. Knowing that, while many of our thoughts are well-formed and quite useful, many do not accurately reflect reality helps us to move beyond many of our fears and insecurities.

 



KU will get cancer center designation, Roberts says

UNIVERSITY OF KANSAS | Senator Roberts posts advance notice

NCI designation as a top-tier research site will open doors to funds for prevention, diagnosis and treatment.

The University of Kansas Cancer Center will receive its valued designation from the National Cancer Institute as a top-tier research institution.

U.S. Sen. Pat Roberts posted the news on his Facebook page Thursday night, and the chairman of the Kansas Board of Regents confirmed it.

Cancer Center Director Roy Jensen said Thursday that a celebration would be premature before the university receives its official notice of grant award.

But Roberts, who as a senator gets the courtesy of advance notice from the federal agency, said KU "has been given a green light and I look forward to a formal announcement…."

Ed McKechnie, chairman of the board of regents, said details of the designation were not yet clear.

"That will all come at the right time," McKechnie said. "It is my understanding we'll be having an announcement in July."

The Board of Regents is the governing body for state universities and community colleges.

The University of Kansas Medical Center has aimed for an NCI designation since 2002. That opens the door to millions of dollars in federal grants as well as private funds for advanced research in cancer prevention, diagnosis and treatment. The economic effect could be in the billions of dollars.

KU applied for the designation in September, after raising and investing about $350 million in the effort by attracting top researchers, developing partnerships and expanding its reach to patients in clinical trials. The university said the effort had created 1,123 jobs and contributed $453 million to the regional economy.

Designation would put KU among well-known cancer research and treatment centers such as M.D. Anderson and Memorial Sloan-Kettering.

Designation as an NCI cancer center also would be a great leap forward in the region's effort to become a hub for life sciences and business.

When KU submitted its application last fall, the National Cancer Institute had 66 designated cancer centers at medical institutions across the country.

To reach Matt Campbell call 816-234-4902 or send email to mcampbell@kcstar.com.





TABS study: Demand for fish oil and vitamin D on the decline; vitamin B still ...

SHELTON, Conn. — TABS Group on Thursday reported a small increase of 2% to $12.2 billion in vitamin sales for the 52 weeks ended in April, according to the “TABS Group Annual Vitamin Study,” now in its fifth year.

This growth came despite the percentage of U.S. vitamin users in 2012 decreasing from 71% to 66%, according to the report, which cited trade-ups, price inflation and the increased usage emanating from current buyers purchasing more vitamins as drivers behind the growth.

While multivitamins remain most popular, with 75% of category buyers purchasing, others include fish oil (43%), calcium (33%), vitamins C and D (both at 32%) and vitamin B (23%).

However, buyer growth in fish oil and vitamin D, two high-growth areas in the past five years, has stopped according to the TABS report. Only vitamin B saw meaningful gains in the 52 weeks ended in April — 23% as compared with 20% in the year-ago period. "Except for vitamin B, there were no areas of growth in attracting additional buyers, which has implications for manufacturers and retailers over the next 18 to 24 months,” noted Kurt Jetta, TABS Group CEO. “We project the category remains relatively flat, with growth coming from trading up existing customers.”

The survey also revealed a shift from specialty retailers toward mainstream. Target, Walgreens, CVS and online sales were all big winners, with Walmart apparently stabilizing share, while catalog and nutritional specialty retailers lost share.

"Longer term, we are bullish on the category and view this as a short-term blip created primarily from unfavorable press,” Jetta said. “Macro consumer trends — aging population, migration toward self-care, higher healthcare costs — point to solid gains over the next 10 years.”

The TABS Group Annual Vitamin Study was conducted among 1,000 representative respondents ages 18 to 75 years.

 


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Vitamin B Levels Higher In Premature Babies, Indicative Of Systemic Immaturity ...

Vitamin B6 Levels Higher In Premature Newborns

Levels of vitamin B, specifically vitamin B6, are found in higher levels in the  cerebrospinal fluid of premature newborns than in full term newborns, indicating an immaturity of the enzymatic system, says a new study published in the July 2012 issue of the journal Pediatrics.

Vitamin B refers to a group of water-soluble vitamins that play important roles in cell metabolism. One specific B vitamin, vitamin B6 or pyridoxine, is necessary for the synthesis of the neurotransmitters serotonin and norepinephrine and for myelin formation. Vitamin B6 is important for healthy brain development and functioning. A deficiency of vitamin B6 can cause seizures in newborns.

In the study "Vitamin B6 Vitamer Concentrations in Cerebrospinal Fluid Differ Between Preterm and Term Newborn Infants," researchers from the Department of Metabolic Diseases and Netherlands Metabolomics Center at the University Medical Center Utrecht in Utrecht, The Netherlands sought to determine whether the vitamin B6 levels in the cerebrospinal fluid of preterm babies different from the levels in full term babies.

A total of 36 newborns, 26 premature and 10 full term, participated in the study. Premature was defined as being born prior to 37 weeks of gestation. Half of the newborns were female, and the other half were male. The youngest baby was born at 26 weeks, the oldest at 41 weeks 1 day.

After the newborns had been admitted to the NICU of the Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands, cerebrospinal fluids were taken from a subcutaneous intraventricular reservoir. The vitamin B6 levels in the fluid samples were then determined by ultra performance liquid chromatography-tandem mass spectrometry.

Levels of vitamin B6 were at least twice as high in the premature babies as in the babies born at full term.

The researchers believe that the differences in levels of vitamin B6 in babies born prematurely versus babies born at term are indicative of an immaturity of the enzymatic system involved in vitamin B6 homeostasis at a lower gestational age. Furthermore, vitamin B6 reference values for older children are inappropriate for application in newborns because the gestational age of the baby must be taken into account.

The results of this study are important for the treatment of epilepsy and vitamin B6 deficiency in newborns. However, more research needs to be conducted on newborn vitamin B6 levels. As Nanda M. Verhoeven-Duif, PhD, of the Department of Metabolic Diseases, University Medical Center Utrecht and one of the authors of the study states in an exclusive comment to The Inquisitr:

"It [This study] is the first time that vitamin B6 is analysed in CSF of newborns. Obtaining CSF is of course only done for diagnostic or therapeutic reasons and we were really happy that we could use these samples for our studies. The results of the study are quite intriguing, why are these concentrations so different in preterm children compared to term children? In our ongoing research project we will try to shed more light on this question."



Camp gives kids with cancer No Worries

TABERNACLE — Natalie Richardson attended Camp No Worries for the first time as an adolescent. Cancer treatments had left her bald, and the 12-year-old arrived at camp wearing a wig.

By the end of the weeklong program, she had gained enough confidence to remove the hairpiece, she said. Getting to know other children with cancer taught her that she wasn't alone in her battle.

Richardson, now 31, is back at the nonprofit Camp No Worries this week as a veteran volunteer serving as its program director. The Hodgkin's lymphoma she was treated for through age 13 has been in remission for years, and the Philadelphia resident's story is encouraging a new generation of campers.

Held at Camp Inawendiwin through a partnership with the Girl Scouts facility, the overnight Camp No Worries is free for children from South Jersey who have had cancer, are living with cancer or who have a sibling with cancer. Sponsored by the YMCA of Burlington and Camden Counties, it costs about $800 for each child's expenses, camp director Chris Callanan said.

"We rely on donations to make sure camp comes back year after year," the Medford native said.

The all-volunteer staff numbers a nearly one-on-one ratio to the campers and includes all types of participants, such as college students, teachers on summer breaks and professional medical personnel. Some used personal vacation time from their regular jobs to volunteer for the week.

A number of similar camps in the United States are devoted to childhood oncology patients, according to Callanan, a Philadelphia resident. Camp No Worries was started in 1994 and is unique in South Jersey, he said.

This year, 86 children ages 6 to 16 are attending the program. Divided into three age groups, they participate in many traditional camp activities, such as team sports and games, swimming, and arts and crafts. Using a time-travel theme, this week's activities included a 1980s-theme dance.

"They will travel around to each of the activities throughout the day," Callanan said. "Each night is a special program."

Medical director Nancy Pirie, a nurse from Medford Lakes, has been with the program since its start. A former oncology nurse, she is an administrator at the Children's Hospital of Philadelphia. Although there are no acutely ill children attending this year, Pirie said previous campers have required medical assistance.

Crystalee Chaparro, 13, of Pennsauken, is among the campers still undergoing chemotherapy treatment. She is fighting leukemia but opted to attend for a third year. During a break from playing Human Pac-Man, Crystalee said the camp allows her to "not think about it" and to have fun.

"If you want to talk about it, there are kids to talk to," she said.

Catie Fisher, 12, has been cancer-free for more than 10 years after battling neuroblastoma. The Burlington Township resident has been attending Camp No Worries for three years with her younger sister, Stephanie. While her classmates at school can't relate, Catie said she has formed friendships with children who have had similar experiences with cancer.

"They understand what it feels like," she said. "Everyone here is nice and welcoming. We're one big happy family."

Siblings of childhood cancer patients, including Crystalee's brother and twin sisters, are as much a priority for Camp No Worries as those battling their illnesses.

Brothers and sisters often are "overlooked" by parents who are more focused on the ill child, according to Callanan. He said siblings are routinely part of the treatment process, often accompanying family members to hospitals and doctors' offices, and helping with care at home.

"At Camp No Worries, they get all the attention they deserve," Callanan said.

Some young siblings interviewed Tuesday said the camp is a "fun" time for them.

Sporting a can tab bracelet she made during an arts and crafts session, Stephanie Fisher, 9, said she gets excited about coming back. In addition to the activities, she said the camp encourages kids to "be yourself."

Medford Lakes resident Kelly Haughey, 9, has been attending the camp for three years. She clutched a stuffed dinosaur from home as she talked about her brother, who has cancer. She said she enjoys "almost everything" about the program, especially making crafts.

Pirie described the camp as a celebration of life for the children.

"When they come here, they're campers. Nobody is really the patient," she said. "That's the really cool part of this."

To make a donation to the program, visit www.campnoworries.org.



DPP to consider charges over cancer deaths

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Controversial alternative treatments given to four cancer patients hastened their deaths, WA’s deputy coroner has found.



Hellfried Sartori

DISGRACED: Hellfried Sartori masterminded an alternative cancer ‘cure’ which the WA deptury coroner ruled hastened the deaths of four WA patients. Picture: Qnpperth/ap
Source: PerthNow


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INQUEST: Dr Alexandra Boyd with her Lawyer Richard Lawson.Picture: Kerris  Berrington
Source: PerthNow


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CONTROVERSIAL alternative treatments given to four cancer patients in Perth hastened their deaths, the State’s deputy coroner has found.


The case will now be referred to the Director of Public Prosecutions to determine whether an offence has been committed, after a lengthy coronial inquest into the deaths of the patients who were treated at the Mosman Park home of Dr Alexandra Boyd,

Deputy State Coroner Evelyn Vicker investigated the deaths of Sandra McCarty, Pia Bosso, Sandra Kokalis, Deborah Gruber, and Carmelo Vinciullo after they all undertook the radical cancer therapy at Kathi Preston Memorial Health Centre – which operated a “clinic” out of Dr Boyd’s home in 2005.

Austrian doctor Hellfried Sartori was the mastermind behind the treatment, and the inquest heard he had his medical licence revoked in several states of the USA and was jailed for practising medicine without a licence.

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The treatment, which the patients were told would cure them of cancer, was an administration of an IV High pH Cancer Therapy, using a range of substances including caesium, the industrial solvent DMSO, and laetrile – all of which are potentially toxic.

Ms McCarty, Ms Bosso, Ms Kokalis, and Ms Gruber all commenced the 12-day IV therapy on May 14, 2005.

Mr Vinciullo commenced the treatment on May 20 2005, but stopped five days later as he was in so much pain he could not continue.

He died on July 1, 2005, with his cancer uncured, and Ms Vicker said his death was from natural causes.

The other four patients died over four days from May 25 to May 28, 2005 – all as a result of the treatment they were given and all still suffering from cancer.

Ms Vicker said four of the seven patients treated at the centre died before they had finished the 12-day course.

WA Police were alerted to the operation of the clinic on May 26 after concerns raised through Fremantle Hospital.

In handing down her findings today, Ms Vicker said the treatment accelerated the deaths of the four women.

“While it is accepted all six cancer patients who died in 2005 had serious, end stage cancer, one of the issues of concern was whether the treatment accelerated any of their deaths,” Ms Vicker wrote in her findings.

“The four women who died, and those who had families involved with the treatment, were given serious misinformation about the risks involved with the treatment itself,

“There is no evidence this particular treatment had any real benefit at all to patients. There is considerable evidence it is dangerous and has a serious risk of accelerating death.”

Ms Vicker said she more concerned that Dr Boyd did not use her conventional medical knowledge to stop the treatment for patients who were clearly suffering than the fact she administered the treatment.

“My biggest concern with Dr Boyd is I simply cannot accept she did not know that part of the treatment involved the administration of caesium and laetrile along with other questionable substances,” Ms Vicker said.

“All patients were anxious to survive. This made them very vulnerable to a claim their cancer could not only be stalled, but most probably cured. All they had to do was believe.”

Ms Vicker said she did not find the public hospitals involved, where the victims eventually died, had any part to play in the deaths.

Her recommendations included restricted access for caesium chloride and other caesium salts, close scrutiny by the Department of Immigration and Citizenship for any Visa application for entry into Australia by Dr Sartori, and that data available from the centre in Perth be comprehensively evaluated to provide education and information to medical health practitioners of the effects of the administration of the substances.

 



Corona Weight Loss Clinic Announces Grand Opening With Free Initial ...

/EINPresswire.com/ Soboba Medical Group’s new weight loss clinic in Corona, California offers HCG, appetite suppressants, lipo-B and vitamin B-12 injections. All programs are supervised by physicians to ensure safety and effectiveness.

Soboba Medical Group, a leader in physician supervised weight loss, is announcing the Grand Opening of its newest clinic in Corona, California. A free initial consultation is being offered to new patients. Corona is the sixth location in Southern California and will serve the Riverside, San Bernardino, and Ontario metropolitan areas. The other Soboba clinics serve the Orange County, Los Angeles, and San Diego areas. Soboba Medical Group was founded by a group of physicians and has been providing physician supervised weight loss solutions for over 40 years.

Soboba’s weight loss programs include HCG, Vitamin B, Lipotropics, Diet Plans and Appetite Suppressants, prescribed by experienced doctors and supported by professional staff.

According to a study by the Mayo Clinic, weight loss should begin by involving a doctor in any weight loss efforts.

At the new Corona Weight Loss Clinic, the weight loss program begins with a free initial consultation with a physician to discuss each patient’s weight loss goals and expectations. Taking into consideration medical history, lifestyle and weight loss goals, the physician will prescribe a weight loss protocol that is comfortable but also leads to success. All programs are tailored to an individual’s needs by knowledgeable physicians and staff who understand that weight loss is not easy, but with safe and effective medications and nutritional guidance, an ideal weight is achievable.

Soboba Medical Group focuses on three components that must be a part of any successful weight loss program.

1. The first step to losing weight is to reduce the number of calories consumed per day. In the initial phase it is important to control hunger cravings. Hunger is a powerful sensation and willpower alone is not enough to get a person from one meal to the next. FDA approved appetite suppressants help to eliminate the hunger sensation.

2. The second step in losing weight is understanding how foods impact body composition. Soboba provides nutritional counseling to ensure that dieters are making the right choices with the foods they eat.

3. The third step in any diet program is support. Weight loss can be challenging and Soboba Medical Group also provides the emotional support needed as each patient goes through the process.

What is HGC and how is it involved in weight loss?
HCG (Human Chorionic Gonadotropin) is a hormone that has been found useful as an additional measure for weight loss. During the 1950s British endocrinologist A.T.W. Simeons noticed a dramatic weight loss in his patients who were being treated with HCG. Following the publication of his studies, HCG has been widely used for weight loss, however, it is not approved by the FDA for weight loss. Learn more about Soboba’s Corona HCG programs.

In 2007, Kevin Trudeau’s book “Weight Loss Cures” advocated the use of HCG in a weight loss protocol. The heightened awareness of HCG generated a large demand for this product, and as an unfortunate consequence a lot of misinformation and ineffective products have come to market. It is important to understand that in addition to the quality of the HCG used, the dosing and protocol of the HCG program is imperative to the success of any weight loss program. All of Soboba’s weight loss programs are doctor supervised to ensure safety and effectiveness.

Soboba Medical Group is owned and directed by Dr. Allen Jay, a board certified internist who has specialized in weight loss and nutritional medicine in Southern California since 1982. With his extensive background in Internal Medicine, Dr. Jay is well qualified to provide safe and effective weight loss treatment. Many other physicians refer patients to Dr. Jay because he believes weight loss should be approached in the context of overall health maintenance. Dr. Jay says that there is a great deal of misinformation about weight loss and that the ‘yo-yo effect’ can be avoided. He emphasizes that, “what people need is sound advice and practical solutions that will help them achieve sustainable results.”

All of the Soboba offices are staffed by trained and experienced physicians and nurses.
Extra care is taken to answer questions and make sure that new patients are thoroughly comfortable and understand how the program works.

Corona Grand Opening Special:
Schedule Free Initial Consultation at the new Corona Weight Loss Clinic,
or call 951-371-5600

Soboba Medical Group’s new Corona Weight Loss office is Located at:
720 Magnolia Avenue, Ste. A-2 in Corona, California.
Corona Weight Loss Directions.

The clinic is easily accessible from Interstate 15 and Highway 91, from Chino, Ontario, Riverside, Moreno Valley, San Bernardino and Lake Elsinore.

Media Contact:
Corona Clinic
Soboba Medical Group
951-371-5600
http://www.sobobaweightloss.com/


PR courtesy of Online PR Media.



Corona Weight Loss Clinic Announces Grand Opening With Free Initial ...

/EINPresswire.com/ Soboba Medical Group’s new weight loss clinic in Corona, California offers HCG, appetite suppressants, lipo-B and vitamin B-12 injections. All programs are supervised by physicians to ensure safety and effectiveness.

Soboba Medical Group, a leader in physician supervised weight loss, is announcing the Grand Opening of its newest clinic in Corona, California. A free initial consultation is being offered to new patients. Corona is the sixth location in Southern California and will serve the Riverside, San Bernardino, and Ontario metropolitan areas. The other Soboba clinics serve the Orange County, Los Angeles, and San Diego areas. Soboba Medical Group was founded by a group of physicians and has been providing physician supervised weight loss solutions for over 40 years.

Soboba’s weight loss programs include HCG, Vitamin B, Lipotropics, Diet Plans and Appetite Suppressants, prescribed by experienced doctors and supported by professional staff.

According to a study by the Mayo Clinic, weight loss should begin by involving a doctor in any weight loss efforts.

At the new Corona Weight Loss Clinic, the weight loss program begins with a free initial consultation with a physician to discuss each patient’s weight loss goals and expectations. Taking into consideration medical history, lifestyle and weight loss goals, the physician will prescribe a weight loss protocol that is comfortable but also leads to success. All programs are tailored to an individual’s needs by knowledgeable physicians and staff who understand that weight loss is not easy, but with safe and effective medications and nutritional guidance, an ideal weight is achievable.

Soboba Medical Group focuses on three components that must be a part of any successful weight loss program.

1. The first step to losing weight is to reduce the number of calories consumed per day. In the initial phase it is important to control hunger cravings. Hunger is a powerful sensation and willpower alone is not enough to get a person from one meal to the next. FDA approved appetite suppressants help to eliminate the hunger sensation.

2. The second step in losing weight is understanding how foods impact body composition. Soboba provides nutritional counseling to ensure that dieters are making the right choices with the foods they eat.

3. The third step in any diet program is support. Weight loss can be challenging and Soboba Medical Group also provides the emotional support needed as each patient goes through the process.

What is HGC and how is it involved in weight loss?
HCG (Human Chorionic Gonadotropin) is a hormone that has been found useful as an additional measure for weight loss. During the 1950s British endocrinologist A.T.W. Simeons noticed a dramatic weight loss in his patients who were being treated with HCG. Following the publication of his studies, HCG has been widely used for weight loss, however, it is not approved by the FDA for weight loss. Learn more about Soboba’s Corona HCG programs.

In 2007, Kevin Trudeau’s book “Weight Loss Cures” advocated the use of HCG in a weight loss protocol. The heightened awareness of HCG generated a large demand for this product, and as an unfortunate consequence a lot of misinformation and ineffective products have come to market. It is important to understand that in addition to the quality of the HCG used, the dosing and protocol of the HCG program is imperative to the success of any weight loss program. All of Soboba’s weight loss programs are doctor supervised to ensure safety and effectiveness.

Soboba Medical Group is owned and directed by Dr. Allen Jay, a board certified internist who has specialized in weight loss and nutritional medicine in Southern California since 1982. With his extensive background in Internal Medicine, Dr. Jay is well qualified to provide safe and effective weight loss treatment. Many other physicians refer patients to Dr. Jay because he believes weight loss should be approached in the context of overall health maintenance. Dr. Jay says that there is a great deal of misinformation about weight loss and that the ‘yo-yo effect’ can be avoided. He emphasizes that, “what people need is sound advice and practical solutions that will help them achieve sustainable results.”

All of the Soboba offices are staffed by trained and experienced physicians and nurses.
Extra care is taken to answer questions and make sure that new patients are thoroughly comfortable and understand how the program works.

Corona Grand Opening Special:
Schedule Free Initial Consultation at the new Corona Weight Loss Clinic,
or call 951-371-5600

Soboba Medical Group’s new Corona Weight Loss office is Located at:
720 Magnolia Avenue, Ste. A-2 in Corona, California.
Corona Weight Loss Directions.

The clinic is easily accessible from Interstate 15 and Highway 91, from Chino, Ontario, Riverside, Moreno Valley, San Bernardino and Lake Elsinore.

Media Contact:
Corona Clinic
Soboba Medical Group
951-371-5600
http://www.sobobaweightloss.com/


PR courtesy of Online PR Media.



Michael Jackson's Tiger, Thriller, Dies of Lung Cancer

LOS ANGELES (AP) — Thriller, a tiger that belonged to Michael Jackson when the entertainer lived at his Neverland ranch, has died of lung cancer at actress-activist Tippi Hedren‘s wildlife preserve in California.

Michael Jackson Handwritten ‘Billie Jean’ Lyrics Fetch $40K at Auction, VMA Nod Nabs $50KRemembering Michael Jackson: 7 Developments After His Death

The 13-year-old, 375-pound tiger died June 11, Hedren said Wednesday. A necropsy was performed and the tiger was cremated. Staff workers will hold a private service when the ashes are buried in a section of the preserve set aside for animals that die there.

Thriller and her brother Sabu were born on Nov. 20, 1998, and lived with Jackson until May 4, 2006, Hedren said. When Jackson left Neverland for good, his veterinarian asked Hedren to take the cats at her Shambala Preserve in Acton, about 50 miles north of Los Angeles.

STORY: 7 Developments Since Michael Jackson’s Death

Other Neverland animals, including giraffes, flamingos, orangutans, elephants and dozens of reptiles, were sent to other sanctuaries in other parts of the country. Shambala didn’t have a lot of room, but Hedren built a $79,000 habitat next to the preserve’s lake and there were trees and a hill and Thriller had a great life with Sabu, she said.

“Thriller was a real piece of work, one gutsy girl. She ruled Sabu’s life. It was humorous to watch the whole relationship. She did things to him that male tigers would normally never allow. She would steal food from him. That’s unheard of. She ruled the roost, was very independent and tough,” Hedren said.

Unlike many of the animals at the preserve, Thriller and Sabu arrived at the compound in excellent health physically and emotionally, Hedren said. There are 15 tigers at the compound, but Sabu is now alone in the habitat he shared with Thriller and he’ll probably stay that way, Hedren said. Tigers are loners in the wild, she explained.

PHOTOS: ‘Glee’ Pays Tribute to the King of Pop

Because Thriller was a famous tiger, she was very popular with visitors and media, Hedren said. “She didn’t care. She was not a diva and didn’t mug for the camera. We all loved her for it.”

Staff was trying to cope with Thriller’s death, Hedren said. “It’s very hard for all of us when these animals go away. Fortunately for Sabu and Thriller, they came in healthy and content. They had no problem with being in quarantine for 30 days. They adjusted so well.”

Most of the animals at Shambala, which requires $75,000 in donations every month to stay open, have trouble adjusting because they have such abusive pasts, Hedren said. Jackson, who died in 2009, often talked about his love of animals, but he never called to check on the tigers and he never sent any money to help pay for their care, Hedren said.

A year after the tigers arrived, Hedren said staff sent a package of photos of Sabu and Thriller and T-shirts and other memorabilia to Jackson’s children, “but we never heard a word back. I just think it’s odd.”

A call to a spokesman for Jackson’s estate was not immediately returned. The estate did not exist when the animals were transferred.



Worried about the side effects of cancer recovery drug Tamoxifen and chose to ...

  • Miss Sewart’s diet bans dairy and meat and contains frozen berries, vegetables and spices such as garlic, turmeric and ginger
  • She says turmeric ‘makes cancer cells commit suicide’
  • Worried about the side effects of cancer recovery drug Tamoxifen and chose to change her diet and exercise routines instead

By
Luke Salkeld and Fiona Macrae

14:30 EST, 24 June 2012

|

01:42 EST, 25 June 2012

Vicky Sewart, pictured in her jewellery shop in Plymouth, opted to treat her condition with a health regime involving exercise and special foods

Vicky Sewart, pictured in her jewellery shop in Plymouth, opted to treat her condition with a health regime involving exercise and special foods

A breast cancer patient refused to take powerful drugs she  was offered to stop the disease returning – and chose to depend on a spicy low-fat diet instead.

Following surgery, Vicky Sewart, 44, was worried about possible side-effects from taking the medication.

So instead, she launched herself into a health regime of exercise and specially chosen foods, including turmeric, which she claims 'makes cancer cells commit suicide'.

Experts have warned there is little scientific evidence to back up her claims.

But Miss Sewart believes that the diet she followed after undergoing chemotherapy, radiotherapy and surgery was a vital part of her recovery from the disease.

Her experience will now form part of an academic study into how lifestyle can affect the body's response to cancer.

After she was diagnosed, Miss Sewart did her own research into which foods might have a positive impact on her recovery.

And following an operation to remove a breast and lymph node four years ago, she told doctors she would not take Tamoxifen during remission but would be following her own 'anti-cancer' diet instead.

She said: 'It's very unusual for breast cancer patients not to take the drug.

'When I told the doctors I didn't want to take it, they just advised me to keep oestrogen out of my body, which is basically what the drug does.

‘The doctors absolutely will not say that the diet is going to do anything to help the cancer in any way, other than to say a healthy diet is going to help in the fight against any disease.

Recovering: A picture of Vicky in Antigua, 2008. Concerned about the side-effects of medical drug Tamoxifen Ms Sewart, 44, designed a vegan, diary free diet which included a range of superfoods from frozen berries to curry spices

Recovering: A picture of Vicky in Antigua, 2008. Concerned about the side-effects of medical drug Tamoxifen Miss Sewart, 44, designed a vegan, diary free diet which included a range of superfoods from frozen berries to curry spices

This was four years ago and I think
attitudes are changing a bit now so that these ideas are running
alongside the more usual treatments.

‘I believe absolutely enormously that my diet has assisted my recovery.'

Explaining her decision not to take
Tamoxifen, she went on: 'It was the worry  of the drugs and the side
effects, I didn't want to have to worry about it, I wanted  to be free.'

Turmeric, a spice used when making curry dishes

Turmeric, a spice used when making curry dishes

The jewellery designer and gallery
owner started her health regime with a mostly organic vegan diet,
cutting out all dairy products, adding plenty of 'super-foods', and
taking moderate exercise.

She said: 'Fresh fruit, vegetables
and juices are great, and frozen berries are fantastic as a super-food.
Turmeric kind of makes cancer cells commit suicide and ginger and garlic
are great to cook with.'

For the past four years, Miss Sewart
has provided blood and urine samples and filled in regular
questionnaires as part of national research into how lifestyle can help
prevent the recurrence of breast cancer after surgery.

The largest study of its kind in the world, it involves 56 hospitals around the UK and 3,400 patients who have had the disease.

The full results will be published next year.

Meanwhile, Miss Sewart, from
Plymouth, is hoping to mark her five-year remission next summer and is
due to marry later this year.

Describing her experience of cancer, she added: 'People can die, or come back from it and enjoy life.

‘You've just got to be thankful you're still around.'

Strawberries is a superfood

Ms Sweart used ginger root in her diet

Vicky Sweart used both frozen berries like strawberries and ginger root in her diet which she claims has helped recovery from breast cancer

However, experts urged other cancer sufferers not to abandon conventional treatments.

Sara Hiom, of Cancer Research UK,
said: 'It's not recommended that alternative therapies are  used in
place of conventional medical therapy.

'There is little scientific or
medical evidence to indicate that alternative therapies are more
effective than the proven treatments used by cancer specialists on the
NHS.

‘We would urge anyone to talk to their specialist if they're contemplating them.'

Dr Steve Kelly, who specialises  in
breast cancer at Derriford Hospital in Plymouth, said: 'Breast cancer
deaths have been going down steadily for over 20 years thanks to
surgery, chemotherapy and radiotherapy.

'But there are three things patients can do to help themselves. It doesn't guarantee survival, but it does help.

'The first is to exercise for 30
minutes, three days a week. The second is to not gain any weight, and
the third is to reduce fat intake.

'These things help to reduce the chance of cancer coming back. For this patient, four years on now, it is still early days.' 

He added: 'My job is not to make people have Tamoxifen, but advise people of the risks and benefits.

‘Treatment comes down to a patient, and height, weight and exercise levels are helpful in making a decision.'

Tamoxifen is Britain's most
widely-used breast cancer drug,  given to more than half of patients to
stop tumours from returning after surgery.

The tablets, which cost as little as
aspirin and are taken for up to five years, also prevent the development
of new tumours in an unaffected breast.

The drug, originally developed as a
contraceptive, is the gold standard treatment for breast cancer and has
been given to millions around the world since the 1980s.

It works by blocking the female sex hormone oestrogen from fuelling the growth of tumours.

Used after surgery, it cuts the odds of the tumour returning by around 30 per cent. However, it does not work in all cases.

In contrast, the evidence for curry
spices such as turmeric beating cancer mainly comes from the study of
cells in a dish – while evidence from the treatment of actual patients
is sparse.

In laboratory studies it seems to be
able to kill cancer cells and prevent more from growing, particularly in
breast, bowel, stomach and skin cancers.

It has also been shown to appear to stop the spread of breast cancer cells to other parts of the body in mice.

Here’s what other readers have said. Why not
debate this issue live on our message boards.

The comments below have not been moderated.

//85% of oncologists admit they would not have conventinal cancer treatment IE chemo and radiation//…..The reason for that is that they understand the discomfort of the treatment and the often very low chance of actually beating the disease. These oncologists have also said they would prefer simply to be made comfortable as they wait to die Don’t recall any saying they’d trust in alternative therapies to cure cancer Their point was that the chance of actually beating the disease was often slight. The quality of life in the last months and years of life was their concern.

I remember the recent report in the press about how colloidal silver is now seriously being accepted as a genuine adjunct to allopathic cancer therapy. In leukemia, colloidal silver killed 98% of blood cancer cells in 24 hours in an American study about 10 years ago. Hydrazine Sulphate, Cesium Chloride, laetrile, oxygen therapies, organic food, exercise, not wearing bras at night (allowing full blood lymph circulation- avoid breast cancer), avoiding chemical birth control and abortions (these affect estrogen levels leading to higher incidence of cancer). Also venus fly trap and cat’s claw combined is a great therapy, also see how hemp is curing people in the YouTube video ‘run from the cure’. There are many other therapies that can all play a part in healing, DMSO, chi gung (gong) , enzyme therapies such as antineoplaston therapy, which was proven very successful by Dr Burzynski, yet heavily suppressed by the FDA in America to protect the pharmaceutical industries financial interests.

I am amazed and saddened at all the red arrows following my comment on how raw milk containing colostrum has been successfully used to cure leukemia. Were the red arrows from mindless trolls, or representatives of the pharmaceutical industry? Because to reject that very genuine therapy and thus discourage leukemia sufferers from considering that alternative is not a good thing. I mentioned this therapy to another acquaintance with leukemia who, like the red arrow people here decided not to try the alternative therapy. He only followed his oncologists advice to stop using all milk produce, he did not even consider that raw milk might really be any different. He was a work colleague of mine who then stuck to standard allopathic care, and very rapidly went downhill, dying a few months later, when, if he had tried what i suggested, he might well have lived, and avoided much suffering.

As a large survey of the benefits of chemotherapy showed a benefit of just 1.4% in the US and 1.6% in Australia, for chemo in breast cancer,[1] turmeric or anything else certainly would have a job to be any worse. And with none of the life-destroying side effects of conventional chemo, I am surprised that more women don’t do a bit of research and take an alternative course.
1. Morgan G, et al. The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies. Clinical Oncology 2004; 16: 549-560.

More than a thousand views of “CANCER – THE FORBIDDEN CURES” since yesterday, just shows there are a lot of open minded people around. Thankyou Vicky for the inspiration.

I am taking Tamoxifen for breast cancer, after having a mastectomy with reconstruction, chemo and radiotherapy. I also include a Turmeric supplement, a Vitamin D supplement, B17 (Apricot Kernels), a good multivitamin and organic fruit and vegetables in my diet (especially red peppers and tomatoes), together with exercise. Tamofixen can cause terrible side-effects, including induced menopause, night sweats, hot flushes and aching limbs. Having followed the conventional treatment regimen, I now wish to include other, beneficial supplements and ‘alternative’ approaches in my fight to stop the cancer returning. This lady has exercised her right to choose how she lives here life following her cancer diagnosis. Good luck to her, and, as for the gentleman who pronounced cancer ‘a myth’, I sincerely hope you are never diagnosed, as you will swiftly discover that there is nothing ‘mythical’ about cancer!

She is right to avoid milk products if they are pasteurized, as all the anti cancer compound contained in it known as colostrum will have been destroyed by pasteurization. Raw milk still contains colostrum however, and cow milk has been successfully used to cure leukemia. An acquaintance of mine had a friend who had leukemia, and he was advised by an ayurvedic medical practitioner to move from England to Vrindavan in India and live on nothing but raw cow milk for one year to cure himself of leukemia, and it worked. Other examples can be found on the internet who have used raw cow milk as therapy for leukemia.

‘The China Study’….read it.

Very interesting, ive heard this before, I was due to have chemo after xmas, but brought a health band from ionic-now.co.uk went to start chemo but they said it had gone down so i had started tumeric as well now and its low enough not to start chemo

Completely Average, Somewhere: Some ‘backwater country’ as you call it may have lower survival rates due to unclean water etc. There is more than one factor at play here. I would change your name to below average if I were you :)

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Cancer victim inspired Obama

Natoma Canfield, the Ohio woman who penned a letter to President Barack Obama that he noted in his remarks to the nation on Thursday and had inspired him to push on with his fight for health care reform, says she got "goose bumps" watching the president after the Supreme Court ruling to uphold the Affordable Care Act.

"I got goose bumps. To think the president of the United States has my letter hanging on the wall. Wow," Canfield told POLITICO in a phone interview minutes after the president concluded his speech from the White House.

Continue Reading

Canfield, who was diagnosed with leukemia about 2½ years ago after battling an early form of cancer for many years, had made national headlines after the White House shared a letter she wrote to the president a few years ago expressing grave concerns about her inability to afford insurance.

In a letter back to Canfield, Obama wrote, "Thanks for your letter. It's because of folks like you that we are still fighting to get health care done!"

In his remarks from the White House Thursday, Obama said he "carried Natoma's story with me every day of the fight to pass this law."

"It reminded me of all the Americans, all across the country, who have had to worry not only about getting sick, but about the cost of getting well," he said. "Natoma is well today. And because of this law, there are other Americans — other sons and daughters, brothers and sisters, fathers and mothers — who will not have to hang their fortunes on chance."

Canfield told POLITICO that she didn't realize the president had her letter framed and hanging at the White House until he said so in his speech Thursday. She got a call from the White House just minutes before Obama stepped in front of the cameras, and said hearing her name on a historic day for the country was an emotional experience.

"I'm just blown away that the president has my letter on his wall. I'm just very proud," she said. "I didn't cry because I don't have any tears now. They were radiated away."

She said her cancer is currently in remission, although she continues to receive treatment and suffers from serious side effects of chemotherapy.

Asked what she would want to say to the president, Canfield said, "I think I would say congratulations. You've done a wonderful job."



Women's lung cancer deaths up in parts of U.S.: study

“Yes, we are making progress in reducing death rates for lung cancer, but there is really a new epidemic and we have to pay attention to increasing death rates in women,” said Ahmedin Jemal, the study’s lead author and a researcher at the American Cancer Society in Atlanta, Georgia.

Lung cancer currently accounts for about one in four cancer deaths in the U.S., making it the top cancer killer, according to the Centers for Disease Control and Prevention.

But lung cancer deaths among both men and women have been steadily declining since the 1990s, a trend usually credited to public health campaigns and state policies, like cigarette taxes and smoking bans, designed to encourage people to quit smoking and discourage young people from starting.

Previous research has shown that women born in 1950 and afterwards are an exception to the recent decline.

Social trends during the 1960s and 1970s, when these women would have taken up smoking in their teens and early adult years, are usually blamed.

But Jemal’s team, with colleagues at the National Cancer Institute, looked at national mortality data to see whether there were any regional patterns as well.

The study is based on data for more than one million U.S. white women aged 35 to 84, who died of lung cancer between 1973 and 2007. The researchers compared 23 states, including 10 in the south and six in the Midwest, and California and New York.

Between the 1970s and 2007, the risk of dying from lung cancer was highest among women born in the 1930s. Rates then dropped off among women born during the following decade.

When it came to baby boomers, post-World War II babies of the late 1940s and 1950s, the numbers of young women dying of lung cancer rose again but only in some states.

In Alabama, for example, deaths per 100,000 increased from 6.9 to 10.7 among women aged 40 to 44. In contrast, deaths fell from 6.1 to 2.8 per 100,000 in the same age group in California.

Similar patterns emerged in other southern states and in the Midwest, while California and New York showed steady declines.

Jemal said that weak anti-smoking political action could be the reason more women are dying in the southern and midwestern states, noting that California was a leader in aggressive tobacco control policies – though he added that tying the decreasing lung cancer death rate to that was still only speculation at this point.



B6 Deficit Tied to CV Disease Risk

By Crystal Phend, Senior Staff Writer, MedPage Today

Low levels of vitamin B6 may play a role in the chronic inflammation that contributes to cardiovascular disease and other common conditions, researchers found.

The top scorers across a panel of inflammatory markers had significantly lower levels of pyridoxal-5-phosphate (PLP) as a plasma marker of vitamin B6 status than the least inflamed individuals in an analysis of the Framingham Offspring cohort study (61 nmol/L versus 80 nmol/L, P0.0001 for trend).

The prevalence of inadequate levels of vitamin B6 marked by PLP under 20 nmol/L roughly doubled across the inflammation tertiles, Lydia Sakakeeny, PhD, of the U.S. Department of Agriculture Human Nutrition Research Center at Tufts University in Boston, and colleagues reported.

“Low vitamin B-6 status, based on plasma concentrations of PLP, has been identified in inflammatory diseases, including cardiovascular disease, rheumatoid arthritis, inflammatory bowel disease, and diabetes,” the group wrote in the July issue of the Journal of Nutrition.

“This study, in combination with past findings, further supports our hypothesis that inflammation is associated with a functional deficiency of vitamin B6,” they added.

The analysis included 2,229 men and women in the 1998-2001 round of examinations in the community-based Framingham Offspring study.

Greater inflammation correlated with lower plasma PLP levels for the primary measure summing scores on standardized values of 13 individual inflammatory markers, including interleukin-6, tumor necrosis factor alpha, and intercellular adhesion molecule-1.

The same was true across various functional groups of inflammation markers.

For both the acute phase reactant markers (C-reactive protein and fibrinogen) and the cytokines (IL-6, TNF factors, and osteoprotegerin), plasma PLP averages went from 76 nmol/L in the lowest inflammatory tertile to 61 nmol/L in the top tertile. Both trends were significant at P0.001.

Likewise for the oxidative stress grouping, plasma PLP averaged 73 nmol/L in the lowest scoring tertile to 63 nmol/L in the highest tertile (P0.0001 for trend).

The selectins — P-selectin and CD40L — tended to follow the same trend but missed statistical significance (P=0.08 for trend).

These multivariate-adjusted associations persisted with additional adjustment for C-reactive protein.

The only marker without a significant correlation to vitamin B6 was serum monocyte chemotactic protein-1 (MCP-1).

High vitamin B6 intake was linked to higher plasma PLP levels, as expected. Yet the most inflamed individuals had significantly lower plasma PLP levels than the least inflamed participants, even after controlling for how much of the water-soluble vitamin people got in their diet.

A sensitivity analysis excluding individuals with preexisting cardiovascular disease or diabetes turned up essentially the same results.

Notably, the same associations with overall inflammation weren’t seen with other B vitamins — plasma folate or vitamin B12, suggesting the link was specific, the researchers noted.

Research into the mechanism for the vitamin B6 link is warranted, they suggested, but “an attractive hypothesis is that the low plasma PLP is a reflection of mobilization of this coenzyme into inflammatory sites.”

The observational findings couldn’t determine causality.

Another limitation was that the population studied had higher average vitamin B6 intake compared with the national population, at 3.1 mg per day from food and supplements versus 1.6 mg in the NHANES study over a similar period.

The largely white population of European ancestry might also have limited generalizability.

The study was supported, in part, by a gift from Pharmavit and by a USDA agreement and a Framingham Heart Study core contract.

The researchers reported having no conflicts of interest to disclose.

Primary source: Journal of Nutrition
Source reference:
Sakakeeny L, et al “Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults” J Nutr 2012; DOI:10.3945/​jn.111.153056.

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Crystal Phend

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Crystal Phend joined MedPage Today in 2006 after roaming conference halls for publications including The Medical Post, Oncology Times, Doctor's Guide, and the journal IDrugs. When not covering medical meetings, she writes from Silicon Valley, just south of the San Francisco fog.

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